The protein encoded by this gene is an inhibitory receptor
found on peripheral mononuclear cells, including NK cells, T cells,
and B cells. Inhibitory receptors regulate the immune response to
prevent lysis of cells recognized as self. The gene is a member of
both the immunoglobulin superfamily and the leukocyte-associated
inhibitory receptor family. The gene maps to a region of 19q13.4
called the leukocyte receptor cluster, which contains at least 29
genes encoding leukocyte-expressed receptors of the immunoglobulin
superfamily.1) Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Immunogen
This LAIR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 177-206 amino acids from the Central region of human LAIR1.
Western blot analysis in K562 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.