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Lamin B1 Antibody

Catalog Number:OM283214
OM283214
Discount Price
OM283214-100ul
1~2 Week
100ul
OM283214-50ul
50ul
OM283214-20ul
20ul
1~2 Week
Product Profile
Product Name Lamin B1 Antibody
Antibody Type Primary Antibodies
Antigen Alias Lamin-B1, LMNB1, LMN2, LMNB
Product description The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Lamin B1 is one of the two B type proteins, B1.1) Martin,C., J. Cell. Sci. 122 (PT 10), 1551-1562 (2009)
Immunogen This Lamin B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 459-488 amino acids from the C-terminal region of human Lamin B1.
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications IHC-PWB
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100:
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Symbol LMNB1
Alternative Names Lamin-B1
LMNB1
LMN2
LMNB
Molecular Weight(MW) 66 kDa
Sequence Similarities Predicted species reactivity based on immunogen sequence: Mouse
Database Links
Entrez Gene 4001
Protein Accession P20700
Application

Application

Lamin B1 Antibody IHC analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Application

Western blot analysis of Lamin B1 antibody in Ramos cell line lysates (35ug/lane)
Application Notes For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100:
Additional Information
Form Liquid
Storage Instructions Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.
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