LETM1 and EF-hand domain-containing protein 1, mitochondrial, Leucine zipper-EF-hand-containing transmembrane protein 1, LETM1
Product description
This gene encodes a protein that is localized to the inner
mitochondrial membrane. The protein functions to maintain the
mitochondrial tubular shapes and is required for normal
mitochondrial morphology and cellular viability. Mutations in this
gene cause Wolf-Hirschhorn syndrome, a complex malformation
syndrome caused by the deletion of parts of the distal short arm of
chromosome 4. Related pseudogenes have been identified on
chromosomes 8, 15 and 19.1) Jiang, D., et al. Science 326(5949):144-147(2009)
Immunogen
This LETM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 577-607 amino acids from the C-terminal region of human LETM1.
Western blot analysis in 293 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.