LIM/homeobox protein Lhx8, LIM homeobox protein 8, LHX8
Product description
Members of the LIM homeobox gene family, such as LHX8,
encode transcription regulators that share common structural
features. They all contain 2 tandemly repeated cysteine-rich
double-zinc finger motifs, called LIM domains, in addition to a
homeodomain. The homeodomain is a DNA-binding domain, and the LIM
domains are essential for regulating the activity of these
molecules by interacting with other proteins. Members of the LIM
homeobox gene family are required for the patterning or the
specification and differentiation of different cell types during
embryonic development (Zhao et al., 1999 [PubMed
10611327]).1) Nikopensius, T., et al. Birth Defects Res. PartClin. Mol. Teratol. 88(9):748-756(2010)
Immunogen
This LHX8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-232 amino acids from the Central region of human LHX8.
Western blot analysis in human placenta tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.