Application
Western blot analysis in mouse lung tissue lysates (35ug/lane).| Product Name | LRP5 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Low-density lipoprotein receptor-related protein 5, LRP-5, LRP5, LR3, LRP7 |
| Product description | This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.1) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) |
| Immunogen | This LRP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1163-1190 amino acids from the C-terminal region of human LRP5. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Mouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | LRP5 |
|---|---|
| Alternative Names | Low-density lipoprotein receptor-related protein 5 LRP-5 LRP5 LR3 LRP7 |
| Molecular Weight(MW) | 179 kDa |
Application
Western blot analysis in mouse lung tissue lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
