Tumor necrosis factor receptor superfamily member 3, Lymphotoxin-beta receptor, Tumor necrosis factor C receptor, Tumor necrosis factor receptor 2-related protein, Tumor necrosis factor receptor type III, TNF-RIII, TNFR-III, LTBR, D12S370, TNFCR, TNFR3, TN
Product description
The protein encoded by this gene is a member of the tumor
necrosis factor (TNF) family of receptors. It is expressed on the
surface of most cell types, including cells of epithelial and
myeloid lineages, but not on T and B lymphocytes. The protein
specifically binds the lymphotoxin membrane form (a complex of
lymphotoxin-alpha and lymphtoxin-beta). The encoded protein and its
ligand play a role in the development and organization of lymphoid
tissue and tranformed cells. Activation of the encoded protein can
trigger apoptosis.1) Cheung, T.C., et al. J. Immunol. 185(3):1949-1958(2010)
Immunogen
This LTBR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-57 amino acids from the N-terminal region of human LTBR.
Western blot analysis in mouse brain tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.