Application
Western blot analysis of MARVELD1 in mouse heart tissue lysate with MARVELD1 antibody at (A) 1 and (B) 2 μg/mL.| Product Name | MARVELD1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | MARVELD1 Antibody: MARVELD1, (MARVEL domain-containing 1), is one of the MARVEL (MAL and related proteins for vesicle trafficking and membrane link) domain-containing proteins. It is a nuclear-localized protein that is widely expressed in normal human tissues. While it has been reported to be overexpressed in colon cancer, MARVELD1 protein levels are generally lower in several primary tumors including ovary, breast, kidney, bladder and liver. This lower level of MARVELD1 expression in tumors is thought to be due to a higher methylation status of the MARVELD1 promoter as treatment of MDA-MB-361 with 5-aza-2'-deoxycytidine restores MARVELD1 expression, suggesting that loss of MARVELD1 expression may contribute to tumorgenicity.1) Wang S, Li Y, Han F, et al. On of MARVELD1, a novel nuclear protein that is down-regulated in multiple cancers and silenced by DNA methylation. Cancer Lett.2009; 282:77-86. |
| Immunogen | MARVELD1 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human MARVELD1. The immunogen is located within the first 50 amino acids of MARVELD1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| MARVELD1 antibody can be used for detection of MARVELD1 by Western blot at 1 - 2 μg/mL. | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | MARVELD1 |
|---|---|
| Alternative Names | MARVELD1 Antibody: MRVLDC1 MARVEL domain-containing protein 1 |
Application
Western blot analysis of MARVELD1 in mouse heart tissue lysate with MARVELD1 antibody at (A) 1 and (B) 2 μg/mL.| Positive Control | 1) Cat. No. 1401 - Mouse Heart Tissue Lysate |
|---|---|
| Application Notes | MARVELD1 antibody can be used for detection of MARVELD1 by Western blot at 1 - 2 μg/mL. |
| Form | Liquid |
|---|---|
| Storage Instructions | MARVELD1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | MARVELD1 Antibody is supplied in PBS containing 0.02% sodium azide. |
