Application
Western blot analysis of anti-MLLT1 Pab in A257 cell line lysate (35ug/lane).Application
Western Blot at 1:2000 dilution Lane 1: Raji whole cell lysates Lane 2: Hela whole cell lysates Lysates/proteins at 20 ug per lane.Application
Western Blot at 1:2000 dilution + Hela whole cell lysates Lysates/proteins at 20 ug per lane.| Product Name | MLLT1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Chromosome band 11q23 is the site of translocations in myeloid and lymphoid acute leukemias, pediatric leukemias, and treatment-induced secondary acute myelogenous leukemia. The translocation breakpoints cluster in a restricted region of the HRX gene resulting in chimeric genes that encode an N-terminal portion of Hrx fused to various partner proteins. Myeloid/lymphoid or mixed-lineage leukemia translocated to 1 (MLLT1) is a nuclear protein with transcriptional transactivation properties that is fused to Hrx in t(11;19) leukemias. The minimal MLLT1 sequence required for transcription activation was narrowed to the C-terminal 90 amino acids.1) Nie, Z., et al., Mol. Cell. Biol. 23(8):2942-2952 (2003). |
| Immunogen | This MLLT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 523-552 amino acids from the C-terminal region of human MLLT1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:2000 | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | MLLT1 |
|---|---|
| Alternative Names | Protein ENL YEATS domain-containing protein 1 MLLT1 ENL LTG19 YEATS1 |
| Molecular Weight(MW) | 62 kDa |
Application
Western blot analysis of anti-MLLT1 Pab in A257 cell line lysate (35ug/lane).
Application
Western Blot at 1:2000 dilution Lane 1: Raji whole cell lysates Lane 2: Hela whole cell lysates Lysates/proteins at 20 ug per lane.
Application
Western Blot at 1:2000 dilution + Hela whole cell lysates Lysates/proteins at 20 ug per lane.| Application Notes | For WB starting dilution is: 1:2000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
