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MMP10 Antibody

Catalog Number:OM284888
OM284888
Discount Price
OM284888-100ul
1~2 Week
100ul
OM284888-50ul
50ul
OM284888-20ul
20ul
1~2 Week
Product Profile
Product Name MMP10 Antibody
Antibody Type Primary Antibodies
Antigen Alias Stromelysin-2, SL-2, Matrix metalloproteinase-10, MMP-10, Transin-2, MMP10, STMY2
Product description Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP10 degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.1) Nagase, H., et al., J. Biol. Chem. 274(31):21491-21494 (1999).
Immunogen This MMP10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 394-423 amino acids from the C-terminal region of human MMP10.
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications IHC-PWB
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100:
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Symbol MMP10
Alternative Names Stromelysin-2
SL-2
Matrix metalloproteinase-10
MMP-10
Transin-2
MMP10
STMY2
Molecular Weight(MW) 54 kDa
Database Links
Entrez Gene 4319
Protein Accession P09238
Application

Application

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. BC = breast carcinoma; HC = hepatocarcinoma.

Application

Western blot analysis of hMMP10-R409 in mouse spleen tissue lysates (35ug/lane)
Application Notes For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100:
Additional Information
Form Liquid
Storage Instructions Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.
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