The product of this gene is a membrane protein expressed
on the oligodendrocyte cell surface and the outermost surface of
myelin sheaths. Due to this localization, it is a primary target
antigen involved in immune-mediated demyelination. This protein may
be involved in completion and maintenance of the myelin sheath and
in cell-cell communication. Alternatively spliced transcript
variants encoding different isoforms have been identified.1) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Immunogen
This MOG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-109 amino acids from the Central region of human MOG.
Western blot analysis in K562 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.