Myeloperoxidase (MPO) is a heme protein synthesized during
myeloid differentiation that constitutes the major component of
neutrophil azurophilic granules. Produced as a single chain
precursor, myeloperoxidase is subsequently cleaved into a light and
heavy chain. The mature myeloperoxidase is a tetramer composed of
2 light chains and 2 heavy chains. This enzyme produces hypohalous
acids central to the microbicidal activity of netrophils. [provided
by RefSeq].1) Banerjee, M., et al. Toxicol. Appl. Pharmacol. 249(1):47-54(2010)
Immunogen
This MPO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 548-575 amino acids from the C-terminal region of human MPO.
Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.