39S ribosomal protein L24, mitochondrial, L24mt, MRP-L24, MRPL24
Product description
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPL24 is a 39S subunit protein which is more than twice the size of its E.coli counterpart (EcoL24).1) Zhang, Z., et al., Genomics 81(5):468-480 (2003).
Immunogen
This MRPL24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 185-214 amino acids from the C-terminal region of human MRPL24.
Western blot analysis of anti-MRPL24 Pab in mouse kidney tissue lysate (35ug/lane)
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.