This gene encodes a member of the muscle segment homeobox
gene family. The encoded protein is a transcriptional repressor
whose normal activity may establish a balance between survival and
apoptosis of neural crest-derived cells required for proper
craniofacial morphogenesis. The encoded protein may also have a
role in promoting cell growth under certain conditions and may be
an important target for the RAS signaling pathways. Mutations in
this gene are associated with parietal foramina 1 and
craniosynostosis type 2.1) Nikopensius, T., et al. Birth Defects Res. PartClin. Mol. Teratol. 88(9):748-756(2010)
Immunogen
This MSX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-148 amino acids from the Central region of human MSX2.
Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.