Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. May be required for AGTR2 cell surface expression. Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation. Isoform 1 inhibits breast cancer cell proliferation, delays the progression of mitosis by prolonging metaphase and reduces tumor growth.1) Kinjo T.,et al.J. Hum. Genet. 45:12-17(2000).
Immunogen
This MTUS1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 183-226 amino acids from human MTUS1.
Western Blot at 1:2000 dilution Lane 1: human brain lysate Lane 2: human lung lysate Lysates/proteins at 20 ug per lane.
Application Notes
For WB starting dilution is: 1:2000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.