Application
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Myc (Phospho-Ser373).Application
Western blot analysis of lysed extracts from A431 cells untreated or treated with EGF using Myc (Phospho-Ser373).| Product Name | Myc (phospho Ser373) Antibody |
|---|---|
| Antibody Type | Tags Antibodies |
| Product description | Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes.1) Baudino T A, et al. (2001) Mol Cell Biol. 21: 691-702. Blackwood E M, et al. (1991) Science. 251:1211-1217. Henriksson M, et al. (1996) Adv Cancer Res. 68: 109-182. Grandori C, et al. (2000) Annu Rev Cell Dev Biol. 16: 653-699. |
| Immunogen | Myc (Phospho-Ser373) antibody was raised against a peptide sequence around phosphorylation site of serine 373 derived from Human Myc. |
| Modification | p-Ser373 |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | MYC |
|---|---|
| Alternative Names | MRTL MYCC c-Myc bHLHe39 NFKB3 c-myc |
| Molecular Weight(MW) | 60 kDa |
| Tissue Specificity | This antibody detects endogenous level of Myc only when phosphorylated at serine 373. |
| Entrez Gene | 4609 |
|---|---|
| Protein Accession | NP_002458.2 |
Application
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Myc (Phospho-Ser373).
Application
Western blot analysis of lysed extracts from A431 cells untreated or treated with EGF using Myc (Phospho-Ser373).| Application Notes | Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
