Application
Antibody used in WB on Human Fetal Pancreas at 5.0 ug/ml.Application
Antibody used in IHC on Human Muscle.| Product Name | NEU1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NEU1, NEU, SIAL1, NANH |
| Product description | NEU1 is a lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A. Mutations in NEU1 gene can lead to sialidosis.The protein encoded by this gene encodes the lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis.1) Hinek, A., (2006) J. Biol. Chem. 281 (6), 3698-3710. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NEU1. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHCWB |
| NEU1 antibody can be used for detection of NEU1 by ELISA at 1:312500. NEU1 antibody can be used for detection of NEU1 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | NEU1 |
|---|---|
| Alternative Names | NEU1 NEU SIAL1 NANH |
| Molecular Weight(MW) | 40 kDa |
Application
Antibody used in WB on Human Fetal Pancreas at 5.0 ug/ml.
Application
Antibody used in IHC on Human Muscle.| Positive Control | 1) Fetal Pancreas Lysate |
|---|---|
| Application Notes | NEU1 antibody can be used for detection of NEU1 by ELISA at 1:312500. NEU1 antibody can be used for detection of NEU1 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store NEU1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
