This gene encodes a member of the neuropilin family of
receptor proteins. The encoded transmembrane protein binds to
SEMA3C protein {sema domain, immunoglobulin domain (Ig), short
basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema
domain, immunoglobulin domain (Ig), short basic domain, secreted,
(semaphorin) 3F}, and interacts with vascular endothelial growth
factor (VEGF). This protein may play a role in cardiovascular
development, axon guidance, and tumorigenesis. Multiple transcript
variants encoding distinct isoforms have been identified for this
gene.1) Rey-Gallardo, A., et al. Glycobiology 20(9):1139-1146(2010)
Immunogen
This Neuropilin-2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 798-827 amino acids from the C-terminal region of human Neuropilin-2.
Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the Neuropilin-2 antibody detected the Neuropilin-2 protein (arrow).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.