Application
Immunohistochemistry staining of NFATC1 in thymus tissue using NFATC1 Antibody.| Product Name | NFATC1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NFATC1, NFATc, NFAT2, NF-ATC, NF-ATC transcription factor, NF-ATc1 |
| Product description | NFAT (nuclear factor of activated T cell transcription factors play critical roles in gene transcription during immune responses. The NFAT complex is made up of NFATc (NFATc1-4) protein and activator protein-1 (AP-1) transcription factor. NFAT proteins are regulated by Ca2+. NFATc1 is a substrate protein phosphatase calcineurin, a critical mediator of calcium signals during T-cell activation. NFATc1 activation requires the translocation of the transcription factor into the nucleus, a process that is mediated by calcineurin. |
| Immunogen | NFATC1 antibody was raised against amino acids 263 - 282 of NFATC1 (Human). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| NFATC1 antibody can be used in ELISA, Western Blot, and immunohistochemistry starting at 5 μg/mL.: |
|
| Species Reactivity | GibbonGorillaHumanMonkey |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Symbol | NFATC1 |
|---|---|
| Alternative Names | NFATC1 NFATc NFAT2 NF-ATC NF-ATC transcription factor NF-ATc1 |
| Tissue Specificity | The amino acid sequence used is 90% homologous in mouse and rat and 100% identical in human NFATc1 A, B, C and E isoforms. The reported amino acid size of NFATc1 isoforms are as follows: A -716 aa, B-825 aa, C-930 aa, and E-812 aa. |
Application
Immunohistochemistry staining of NFATC1 in thymus tissue using NFATC1 Antibody.| Application Notes | NFATC1 antibody can be used in ELISA, Western Blot, and immunohistochemistry starting at 5 μg/mL.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | NFATC1 antibody can be stored short term 4 ˚C. For long term storage aliquot and store at -20 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, 0.05% BSA, 0.05% sodium azide. |
