Application
Immunohistochemistry staining of NFKB2 in thymus tissue using NFKB2 Antibody.| Product Name | NFKB2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NFKB2, DNA-binding factor KBF2, LYT10, Oncogene Lyt-10, p52, LYT-10, NF-kB2, p105, H2TF1 |
| Product description | NFκB was originally identified as a factor that binds to the immunoglobulin kappa light chain enhancer in B cells. It was subsequently found in non-B cells in an inactive cytoplasmic form consisting of NFκB bound to IkB. NFκB was originally identified as a heterodimeric DNA binding protein complex consisting of p65 (RelA) and p50 (NFκB1) subunits. Other identified subunits include p52 (NFκB2), c-Rel, and RelB. The p65, cRel, and RelB subunits are responsible for transactivation. The p50 and p52 subunits possess DNA binding activity but limited ability to transactivate. p52 has been reported to form transcriptionally active heterodimers with the NFκB subunit p65, similar to p50/p65 heterodimers. The heterodimers of p52/p65 and p50/p65 are regulated by physical inactivation in the cytoplasm by an inhibitor called IkB-a. IkB-a binds to the p65 subunit, preventing nuclear localization and DNA binding. Low levels of p52 and p50 homodimers can also exist in cells. |
| Immunogen | NFKB2 antibody was raised against a peptide near the N-Terminus of NFKB2 (Human). |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHCIPWB |
| NFKB2 antibody can be used in ELISA, and immunohistochemistry starting at 20 μg/mL.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | NFKB2 |
|---|---|
| Alternative Names | NFKB2 DNA-binding factor KBF2 LYT10 Oncogene Lyt-10 p52 LYT-10 NF-kB2 p105 H2TF1 |
Application
Immunohistochemistry staining of NFKB2 in thymus tissue using NFKB2 Antibody.| Application Notes | NFKB2 antibody can be used in ELISA, and immunohistochemistry starting at 20 μg/mL.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store NFKB2 antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide. |
