Nuclear transcription factor Y subunit gamma, CAAT box DNA-binding protein subunit C, Nuclear transcription factor Y subunit C, NF-YC, Transactivator HSM-1/2, NFYC
Product description
This gene encodes one subunit of a trimeric complex
forming a highly conserved transcription factor that binds with
high specificity to CCAAT motifs in the promoters of a variety of
genes. The encoded protein, subunit C, forms a tight dimer with the
B subunit, a prerequisite for subunit A association. The resulting
trimer binds to DNA with high specificity and affinity. Subunits B
and C each contain a histone-like motif. Multiple transcript
variants encoding different isoforms have been found for this gene.1) Ichikawa, S., et al. J. Bone Miner. Res. 25(8):1821-1829(2010)
Immunogen
This NFYC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 100-129 amino acids from the N-terminal region of human NFYC.
Nuclear transcription factor Y subunit gamma CAAT box DNA-binding protein subunit C Nuclear transcription factor Y subunit C NF-YC Transactivator HSM-1/2 NFYC
Molecular Weight(MW)
50 kDa
Sequence Similarities
Predicted species reactivity based on immunogen sequence: Bovine
Western blot analysis in HepG2 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.