Application
Antibody used in WB on Human A172 at 1.25 ug/ml.Application
Antibody used in IHC on Human kidney.| Product Name | NR3C2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NR3C2, MCR, MGC133092, MLR, MR, NR3C2VIT |
| Product description | NR3C2 is a receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. It binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.1) Liu, G., (2006) Biochem. Biophys. Res. Commun. 342 (4), 1291-1296. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR3C2. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHCWB |
| NR3C2 antibody can be used for detection of NR3C2 by ELISA at 1:312500. NR3C2 antibody can be used for detection of NR3C2 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | NR3C2 |
|---|---|
| Alternative Names | NR3C2 MCR MGC133092 MLR MR NR3C2VIT |
| Molecular Weight(MW) | 107 kDa |
Application
Antibody used in WB on Human A172 at 1.25 ug/ml.
Application
Antibody used in IHC on Human kidney.| Positive Control | 1) A172 Cell Lysate |
|---|---|
| Application Notes | NR3C2 antibody can be used for detection of NR3C2 by ELISA at 1:312500. NR3C2 antibody can be used for detection of NR3C2 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store NR3C2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
