Application
Immunohistochemistry staining of NPM1 in skin tissue using NPM1 Antibody.| Product Name | Nucleophosmin Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NPM1, NPM, Nucleolar phosphoprotein B23, Nucleolar protein NO38, Numatrin, B23, Nucleophosmin |
| Product description | NPM1 is a ubiquitously expressed nucleolar protein that shuttles between the nucleus and cytoplasm. It is implicated in multiple functions, including ribosomal protein assembly and transport, control of centrosome duplication, and regulation of the tumor suppressor ARF. NPM1 mutations that relocalize NPM1 from the nucleus into the cytoplasm are associated with development of acute myeloid leukemia. |
| Immunogen | Nucleophosmin antibody was raised against a modified peptide of Nucleophosmin (Human). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| Nucleophosmin antibody can be used in ELISA, Western Blot, immunohistochemistry starting at 10 μg/mL, and immunoprecipitation: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | NPM1 |
|---|---|
| Alternative Names | NPM1 NPM Nucleolar phosphoprotein B23 Nucleolar protein NO38 Numatrin B23 Nucleophosmin |
| Tissue Specificity | pThr234/Thr237 |
Application
Immunohistochemistry staining of NPM1 in skin tissue using NPM1 Antibody.| Application Notes | Nucleophosmin antibody can be used in ELISA, Western Blot, immunohistochemistry starting at 10 μg/mL, and immunoprecipitation: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store Nucleophosmin antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, 0.09% sodium azide, 50% glycerol. BSA is present at 1 mg/mL final concentration (USA origin). |
