Application
Western blot analysis of NUP155 in P815 cell lysate with NUP155 antibody at (A) 0.5 and (B) 1 μg/mL.| Product Name | NUP155 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NUP155 Antibody: N155, KIAA0791, Nuclear pore complex protein Nup155, 155 kDa nucleoporin |
| Product description | NUP155 Antibody: The nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm. One protein in this assembly is the nucleoporin (NUP)-155, which is localized symmetrically to both the nucleoplasmic and cytoplasmic faces of the NPC. NUP155 has been reported to interact with both NUP35 and the mRNA export factor Gle1, but the functions of these interactions are still unknown. NUP155 has also been shown to be required for NPC assembly and nuclear envelope (NE) membrane fusion. NUP155 is recruited late in NE formation, suggesting that NUP155 defines an essential late step in NE assembly. NUP155 has recently been identified as an HIV dependency factor (HDF), suggesting that NUP155 may be an important drug target in HIV treatment. At least two isoforms of NUP155 are known to exist.1) Tran EJ and Wente SR. Dynamic nuclear pore complex: life on the edge. Cell2006; 125:1041-53. |
| Immunogen | NUP155 antibody was raised against a 18 amino acid synthetic peptide from near the carboxy terminus of human NUP155. The immunogen is located within the last 50 amino acids of NUP155. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| NUP155 antibody can be used for detection of NUP155 by Western blot at 0.5 - 1 μg/mL.: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | NUP155 |
|---|---|
| Alternative Names | NUP155 Antibody: N155 KIAA0791 Nuclear pore complex protein Nup155 155 kDa nucleoporin |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Rat: (100%) |
Application
Western blot analysis of NUP155 in P815 cell lysate with NUP155 antibody at (A) 0.5 and (B) 1 μg/mL.| Positive Control | 1) Cat. No. 1286 - P815 Cell Lysate |
|---|---|
| Application Notes | NUP155 antibody can be used for detection of NUP155 by Western blot at 0.5 - 1 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | NUP155 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | NUP155 Antibody is supplied in PBS containing 0.02% sodium azide. |
