OCIAD2 Antibody: OCIA domain-containing protein 2, Ovarian carcinoma immunoreactive antigen-like protein
Product description
OCIAD2 Antibody: OCIAD2 was identified by its sequence similarity with OCIAD1, and together OCIAD1 and OCIAD2 form the OCIA domain family. OCIAD2 mRNA was found to be expressed at higher levels in invasive adenocarcinoma mixed subtype with bronchioloalveolar carcinoma component (BAC) of the lung. Loss of OCIAD2 expression was significantly correlated with lymphatic invasion, blood vessel invasion, and lymph node metastasis, indicating that OCIAD2 may play a role in cell adhesion and prevention of cell migration. While the function of OCIAD2 is still unknown, its expression in adenocarcinoma with BAC component is significantly associated with a favorable prognosis and may serve as a marker for selecting tumors that are treatable by limited surgery.1) Strausberg RL, Feingold EA, Grouse LH, et al. Mammalian gene collection program team. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. USA2002; 99:16899-903.
Immunogen
OCIAD2 antibody was raised against an 18 amino acid synthetic peptide from near the carboxy terminus of human OCIAD2. The immunogen is located within the last 50 amino acids of OCIAD2.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAIFWB
OCIAD2 antibody can be used for detection of OCIAD2 by Western blot at 0.5 - 1 μg/mL. Antibody can also be used for immunoflourescence starting at 5 μg/mL. For immunofluorescence start at 5 μg/mL.:
Immunofluorescence of OCIAD2 in A549 cells with OCIAD2 antibody at 5 μg/mL.
Application
Western blot analysis of OCIAD2 in A549 cell lysate with OCIAD2 antibody at (A) 0.5 and (B) 1 μg/mL.
Positive Control
1) Cat. No. 1203 - A549 Cell Lysate
Application Notes
OCIAD2 antibody can be used for detection of OCIAD2 by Western blot at 0.5 - 1 μg/mL. Antibody can also be used for immunoflourescence starting at 5 μg/mL. For immunofluorescence start at 5 μg/mL.:
Additional Information
Form
Liquid
Storage Instructions
OCIAD2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer
OCIAD2 Antibody is supplied in PBS containing 0.02% sodium azide.