The oxytocin receptor belongs to the vasopressin/oxytocin family of GPCRs because it binds similar cyclic nonapeptide hormones. The oxytocin receptor functions primarily during labor and lactation. There is a dramatic increase in the number of oxytocin receptors just before the onset of labor causing the uterine muscles to become exceedingly sensitive to oxytocin. The activated oxytocin receptor causes an inward membrane current that results in smooth muscle contraction during labor and milk ejection during lactation. This receptor also plays a role in natriuresis, kaliuresis and may have an antistress effect.
Immunogen
Oxytocin Receptor antibody was raised against a peptide located in the C-Terminal cytoplasmic domain of Oxytocin Receptor (Human).
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAIHC
Oxytocin Receptor antibody can be used in immunohistochemistry starting at 8 μg/mL.:
Immunohistochemistry staining of Oxytocin receptor in uterus, pregnant tissue using Oxytocin receptor Antibody.
Application Notes
Oxytocin Receptor antibody can be used in immunohistochemistry starting at 8 μg/mL.:
Additional Information
Form
Liquid
Storage Instructions
Oxytocin Receptor antibody should be stored long term (months) at -80 ˚C and short term (days) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles.