P2Y purinoceptor 1, P2Y1, ATP receptor, Purinergic receptor, P2RY1
Product description
The product of this gene belongs to the family of
G-protein coupled receptors. This family has several receptor
subtypes with different pharmacological selectivity, which overlaps
in some cases, for various adenosine and uridine nucleotides. This
receptor functions as a receptor for extracellular ATP and ADP. In
platelets binding to ADP leads to mobilization of intracellular
calcium ions via activation of phospholipase C, a change in
platelet shape, and probably to platelet aggregation. [provided by
RefSeq].1) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Immunogen
This P2RY1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 231-260 amino acids from the Central region of human P2RY1.
Western blot analysis in NCI-H292 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.