PANK1 belongs to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA.1) Ramaswamy, G., et al., J. Lipid Res. 45(1):17-31 (2004).
Immunogen
This PANK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-105 amino acids from the N-terminal region of human PANK1.
Western blot analysis of hPANK1-R90 in MCF-7 cell line and mouse spleen tissue lysates (35ug/lane)
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.