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PAX8 Antibody

Catalog Number:OM287452
OM287452
Discount Price
OM287452-100ul
1~2 Week
100ul
OM287452-50ul
50ul
OM287452-20ul
20ul
1~2 Week
Product Profile
Product Name PAX8 Antibody
Antibody Type Primary Antibodies
Antigen Alias PAX8,
Product description PAX8 is a member of the paired box (PAX) family of transcription factors. Members of this family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in its gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas.This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins which contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.1) Kimura, K., (2006) Genome Res. 16 (1), 55-65.
Immunogen Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PAX8.
Key Feature
Clonality Polyclonal
Host Species Rabbit
Tested Applications ELISAWB
PAX8 antibody can be used for detection of PAX8 by ELISA at 1:62500. PAX8 antibody can be used for detection of PAX8 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Species Reactivity DogHumanMouseRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol PAX8
Alternative Names PAX8
Molecular Weight(MW) 48 kDa, 42 kDa, 43 kDa, 35 kDa, 31 kDa
Database Links
Entrez Gene 7849
Protein Accession NP_003457
Application

Application

Antibody used in WB on Human HepG2 at 0.2-1 ug/ml.
Positive Control 1) Cat. No. 1211 - HepG2 Cell Lysate
Application Notes PAX8 antibody can be used for detection of PAX8 by ELISA at 1:62500. PAX8 antibody can be used for detection of PAX8 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form Liquid
Storage Instructions For short periods of storage (days) store at 4˚C. For longer periods of storage, store PAX8 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
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