PACE4 is a Serine S8 type protease that cleaves precursor proteins at paired basic amino acid processing sites. Several PACE4 substrates have been identified, including transforming growth factor beta-related proteins, proalbumin and von Willebrand factor. At least eight alternatively spliced transcript variants encoding different isoforms have been reported. In mouse, PACE4 has been shown to increase tumor cell invasiveness, and thus enhance tumor progression.
Immunogen
PCSK6 antibody was raised against a peptide located near the internal domain of PCSK6 (Human).
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
WB
PCSK6 antibody can be used in ELISA, and immunohistochemistry starting at 20 μg/mL.: