Phosphodiesterase 1C is a cAMP/cGMP dual-specific, calcium/calmodullin-dependent phosphodiesterase. PDE1C has been shown to affect vascular smooth muscle proliferation and atherosclerosis, insulin secretion regulation, spermatozoa development, and erectile dysfunction. At least five PDE1C isoforms have been reported, the expression of which are regulated in a tissue/cell-specific manner.
Immunogen
PDE1C antibody was raised against a peptide located in the C-Terminal domain of PDE1C (Human).
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
IHC
PDE1C antibody can be used in immunohistochemistry starting at 10 μg/mL, and flow cytometry.: