Application
Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with PDE8A antibody (L572), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.Application
Western blot analysis of PDE8A Antibody (L572) in HL60 cell line lysates (35ug/lane)| Product Name | PDE8A Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A, PDE8A |
| Product description | PDE8A plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase, which has a high affinity for cAMP, may be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development.1) Wu,P., Proc. Natl. Acad. Sci. U.S.A. 101 (51), 17634-17639 (2004) |
| Immunogen | This PDE8A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 557-587 amino acids from the Central region of human PDE8A. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Symbol | PDE8A |
|---|---|
| Alternative Names | High affinity cAMP-specific and IBMX-insensitive 3' 5'-cyclic phosphodiesterase 8A PDE8A |
| Molecular Weight(MW) | 93 kDa |
Application
Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with PDE8A antibody (L572), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
Application
Western blot analysis of PDE8A Antibody (L572) in HL60 cell line lysates (35ug/lane)| Application Notes | For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
