Application
PDGFC antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.Application
Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).| Product Name | PDGFC Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Platelet-derived growth factor C, PDGF-C, Fallotein, Spinal cord-derived growth factor, SCDGF, VEGF-E, Platelet-derived growth factor C, latent form, PDGFC latent form, Platelet-derived growth factor C, receptor-binding form, PDGFC receptor-binding form, P |
| Product description | Platelet-derived growth factor C (PDGFC) is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. PDGFC seems to form only homodimers, where the dimers are connected by disulfide bonds. It differs from the platelet-derived growth factor alpha (PDGFA) and beta (PDGFB) in having an unusual N-terminal domain, the CUB domain.1) Fang, L., et al., Arterioscler. Thromb. Vasc. Biol. 24(4):787-792 (2004). Clark, H.F., et al., Genome Res. 13(10):2265-2270 (2003). Eitner, F., et al., J. Am. Soc. Nephrol. 14(5):1145-1153 (2003). Reigstad, L.J., et al., J. Biol. Chem. 278(19):17114-17120 (2003). Zwerner, J.P., et al., Oncogene 21(24):3847-3854 (2002). |
| Immunogen | This PDGFC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-103 amino acids from the N-terminal region of human PDGFC. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Symbol | PDGFC |
|---|---|
| Alternative Names | Platelet-derived growth factor C PDGF-C Fallotein Spinal cord-derived growth factor SCDGF VEGF-E Platelet-derived growth factor C latent form PDGFC latent form Platelet-derived growth factor C receptor-binding form PDGFC receptor-binding form P |
| Molecular Weight(MW) | 39 kDa |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Chicken |
Application
PDGFC antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Application
Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
