This gene encodes a protein with significant sequence
similarity to the ligand binding domain of platelet-derived growth
factor receptor beta. Mutations in this gene, or deletion of a
chromosomal segment containing this gene, are associated with
sporadic hepatocellular carcinomas, colorectal cancers, and
non-small cell lung cancers. This suggests this gene product may
function as a tumor suppressor.1) Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Immunogen
This PDGFRL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-44 amino acids from the N-terminal region of human PDGFRL.
Western blot analysis in mouse heart tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.