Application
Antibody used in WB on Human HepG2 at 5.0 ug/ml.| Product Name | PDSS1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PDSS1, COQ1, MGC70953, RP13-16H11.3, TPRT, TPT, hDPS1, DPS, SPS, TPT 1, COQ10D2 |
| Product description | PDSS1 is an enzyme that elongates the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. PDSS1 catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. The protein may be peripherally associated with the inner mitochondrial membrane, though no transit peptide has been definitively identified to date. Defects in PDSS1 gene are a cause of coenzyme Q10 deficiency.The protein encoded by this gene is an enzyme that elongates the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. The protein may be peripherally associated with the inner mitochondrial membrane, though no transit peptide has been definitively identified to date. Defects in this gene are a cause of coenzyme Q10 deficiency.1) Mollet, J., (2007) J. Clin. Invest. 117 (3), 765-772. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PDSS1. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| PDSS1 antibody can be used for detection of PDSS1 by ELISA at 1:312500. PDSS1 antibody can be used for detection of PDSS1 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | PDSS1 |
|---|---|
| Alternative Names | PDSS1 COQ1 MGC70953 RP13-16H11.3 TPRT TPT hDPS1 DPS SPS TPT 1 COQ10D2 |
| Molecular Weight(MW) | 46 kDa |
Application
Antibody used in WB on Human HepG2 at 5.0 ug/ml.| Positive Control | 1) Cat. No. 1211 - HepG2 Cell Lysate |
|---|---|
| Application Notes | PDSS1 antibody can be used for detection of PDSS1 by ELISA at 1:312500. PDSS1 antibody can be used for detection of PDSS1 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store PDSS1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
