Application
Formalin-fixed and paraffin-embedded human testis tissue reacted with PDX1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.Application
Western blot analysis of PDX1 using rabbit polyclonal PDX1 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PDX1 gene (Lane 2).| Product Name | PDX1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Pancreas/duodenum homeobox protein 1, PDX-1, Glucose-sensitive factor, GSF, Insulin promoter factor 1, IPF-1, Insulin upstream factor 1, IUF-1, Islet/duodenum homeobox-1, IDX-1, Somatostatin-transactivating factor 1, STF-1, PDX1, IPF1, STF1 |
| Product description | PDX1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. This nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in the gene encoding PDX1 are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).1) Ma,J., Carcinogenesis 29 (7), 1327-1333 (2008) |
| Immunogen | This PDX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-69 amino acids from the N-terminal region of human PDX1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PDX1 |
|---|---|
| Alternative Names | Pancreas/duodenum homeobox protein 1 PDX-1 Glucose-sensitive factor GSF Insulin promoter factor 1 IPF-1 Insulin upstream factor 1 IUF-1 Islet/duodenum homeobox-1 IDX-1 Somatostatin-transactivating factor 1 STF-1 PDX1 IPF1 STF1 |
| Molecular Weight(MW) | 31 kDa |
Application
Formalin-fixed and paraffin-embedded human testis tissue reacted with PDX1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
Application
Western blot analysis of PDX1 using rabbit polyclonal PDX1 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PDX1 gene (Lane 2).| Application Notes | For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
