Application
Western blot analysis in T47D cell line lysates (35ug/lane).Application
PGR/PR Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.| Product Name | PGR/PR Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Progesterone receptor, PR, Nuclear receptor subfamily 3 group C member 3, PGR, NR3C3 |
| Product description | This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform A has not been clearly determined.1) Geradts, J., et al. Cancer Invest. 28(9):969-977(2010) |
| Immunogen | This PGR/PR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 349-377 amino acids from the Central region of human PGR/PR. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PGR |
|---|---|
| Alternative Names | Progesterone receptor PR Nuclear receptor subfamily 3 group C member 3 PGR NR3C3 |
| Molecular Weight(MW) | 99 kDa |
Application
Western blot analysis in T47D cell line lysates (35ug/lane).
Application
PGR/PR Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.| Application Notes | For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
