GPI transamidase component PIG-T, Phosphatidylinositol-glycan biosynthesis class T protein, PIGT
Product description
This gene encodes a protein that is involved in
glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The
GPI-anchor is a glycolipid found on many blood cells and serves to
anchor proteins to the cell surface. This protein is an essential
component of the multisubunit enzyme, GPI transamidase. GPI
transamidase mediates GPI anchoring in the endoplasmic reticulum,
by catalyzing the transfer of fully assembled GPI units to
proteins. Several transcript variants encoding different isoforms
have been found for this gene.1) Li, H.L., et al. FEBS Lett. 580(7):1723-1728(2006)
Immunogen
This PIGT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 392-421 amino acids from the C-terminal region of human PIGT.
Western blot analysis in NCI-H292 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.