Phosphoinositide-specific phospholipase C (PLC) acts as a
signal transducer that generates 2 second messengers,
diacylglycerol and inositol 1,4,5-trisphosphate, by hydrolyzing
inositol phospholipids. PLC comprises a diverse family of enzymes
that differ in structure and tissue distribution (Berridge, 1993
[PubMed 8381210]).1) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Immunogen
This PLCD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-163 amino acids from the N-terminal region of human PLCD1.
Western blot analysis in HL-60 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.