This gene encodes a member of the sialomucin protein
family. The encoded protein was originally identified as an
important component of glomerular podocytes. Podocytes are highly
differentiated epithelial cells with interdigitating foot processes
covering the outer aspect of the glomerular basement membrane.
Other biological activities of the encoded protein include: binding
in a membrane protein complex with Na+/H+ exchanger regulatory
factor to intracellular cytoskeletal elements, playing a role in
hematopoetic cell differentiation, and being expressed in vascular
endothelium cells and binding to L-selectin.1) Schopperle, W.M., et al. Biochem. Biophys. Res. Commun. 398(3):372-376(2010)
Immunogen
This PODXL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 410-439 amino acids from the C-terminal region of human PODXL.
Western Blot at 1:1000 dilution + Hela whole cell lysate Lysates/proteins at 20 ug per lane.
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.