Application
Antibody used in IHC on Human Intestine.Application
Antibody used in WB on Human HepG2 cells at 2.5 ug/ml.| Product Name | PPIA Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | PPIA is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. PPIA is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions.The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a cyclosporin binding-protein. It may play a role in cyclosporin A-mediated immunosuppression. This protein can interact with several HIV proteins including p55 gag, Vpr, and capsid protein. It has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported. Three alternatively spliced transcript variants encoding two distinct isoforms have been observed.1) Sokolskaja, E., (2006) J. Virol. 80 (6), 2855-2862. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PPIA. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHCWB |
| PPIA antibody can be used for detection of PPIA by ELISA at 1:312500. PPIA antibody can be used for detection of PPIA by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. | |
| Species Reactivity | DogHumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | PPIA |
|---|---|
| Alternative Names | PPIA CYPA CYPH MGC117158 MGC12404 MGC23397 HEL-S-69p |
| Molecular Weight(MW) | 18 kDa |
Application
Antibody used in IHC on Human Intestine.
Application
Antibody used in WB on Human HepG2 cells at 2.5 ug/ml.| Positive Control | 1) Cat. No. 1211 - HepG2 Cell Lysate |
|---|---|
| Application Notes | PPIA antibody can be used for detection of PPIA by ELISA at 1:312500. PPIA antibody can be used for detection of PPIA by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store PPIA antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
