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PRMT2 Antibody

Catalog Number:OM288853
OM288853
Discount Price
OM288853-100ul
1~2 Week
100ul
OM288853-50ul
50ul
OM288853-20ul
20ul
1~2 Week
Product Profile
Product Name PRMT2 Antibody
Antibody Type Primary Antibodies
Antigen Alias Protein arginine N-methyltransferase 2, 211-, Histone-arginine N-methyltransferase PRMT2, PRMT2, HMT1, HRMT1L1
Product description Arginine methylation is an irreversible post translational modification which has only recently been linked to protein activity. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These protein include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Outside of these domains, epitopes were identified and antibodies against all 7 PRMT members have been developed.1) Qi, C., et al., J. Biol. Chem. 277(32):28624-28630 (2002).
Immunogen This PRMT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-375 amino acids from the C-terminal region of human PRMT2.
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WB
For WB starting dilution is: 1:1000:
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Symbol PRMT2
Alternative Names Protein arginine N-methyltransferase 2
211-
Histone-arginine N-methyltransferase PRMT2
PRMT2
HMT1
HRMT1L1
Molecular Weight(MW) 49 kDa
Database Links
Entrez Gene 3275
Protein Accession P55345
Application

Application

Western blot analysis of PRMT2 using rabbit polyclonal PRMT2 Antibody (L359) using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PRMT2 gene.

Application

Western blot analysis of anti-PRMT2 Pab in whole HL60 cell lysate was detected using purified Pab.
Application Notes For WB starting dilution is: 1:1000:
Additional Information
Form Liquid
Storage Instructions Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.
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