Application
Antibody used in WB on Human 721_B cells at 0.2-1 ug/ml.| Product Name | PSMC3IP Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PSMC3IP, GT198, HOP2, TBPIP, ODG3, HUMGT198A |
| Product description | PSMC3IP plays an important role in meiotic recombination. It stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis. The complex PSMC3IP/MND1 binds DNA, stimulates the recombinase activity of DMC1 as well as DMC1 D-loop formation from double-strand DNA. This complex stabilizes presynaptic RAD51 and DMC1 filaments formed on single strand DNA to capture double-strand DNA. This complex stimulates both synaptic and presynaptic critical steps in RAD51 and DMC1-promoted homologous pairing. It may inhibit HIV-1 viral protein TAT activity and modulate the activity of proteasomes through association with PSMC3.1) Enomoto, R., (2006) J. Biol. Chem. 281 (9), 5575-5581. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PSMC3IP. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| PSMC3IP antibody can be used for detection of PSMC3IP by ELISA at 1:1562500. PSMC3IP antibody can be used for detection of PSMC3IP by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PSMC3IP |
|---|---|
| Alternative Names | PSMC3IP GT198 HOP2 TBPIP ODG3 HUMGT198A |
| Molecular Weight(MW) | 24 kDa |
Application
Antibody used in WB on Human 721_B cells at 0.2-1 ug/ml.| Positive Control | 1) 721_B Cell Lysate |
|---|---|
| Application Notes | PSMC3IP antibody can be used for detection of PSMC3IP by ELISA at 1:1562500. PSMC3IP antibody can be used for detection of PSMC3IP by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store PSMC3IP antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
