Phosphatidylserine (PS) accounts for 5 to 10% of cell
membrane phospholipids. In addition to its role as a structural
component, PS is involved in cell signaling, blood coagulation, and
apoptosis. PS is synthesized by a calcium-dependent base-exchange
reaction catalyzed by PS synthases (EC 2.7.8.8), like PTDSS1, that
exchange L-serine for the polar head group of phosphatidylcholine
(PC) or phosphatidylethanolamine (PE) (Sturbois-Balcerzak et al.,
2001 [PubMed 11084049]).1) Rose, J. Phd, et al. Mol. Med. (2010) In press :
Immunogen
This PTDSS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 390-418 amino acids from the C-terminal region of human PTDSS1.
Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.