Application
Western blot analysis in K562 cell line lysates (35ug/lane).| Product Name | PTF1A Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Pancreas transcription factor 1 subunit alpha, Class A basic helix-loop-helix protein 29, bHLHa29, Pancreas-specific transcription factor 1a, bHLH transcription factor p48, p48 DNA-binding subunit of transcription factor PTF1, PTF1-p48, PTF1A, BHLHA29, PTF |
| Product description | This gene encodes a protein that is a component of the pancreas transcription factor 1 complex (PTF1) and is known to have a role in mammalian pancreatic development. The protein plays a role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. The protein is thought to be involved in the maintenance of exocrine pancreas-specific gene expression including elastase 1 and amylase. Mutations in this gene cause cerebellar agenesis and loss of expression is seen in ductal type pancreas cancers.1) Meredith, D.M., et al. J. Neurosci. 29(36):11139-11148(2009) |
| Immunogen | This PTF1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 287-316 amino acids from the C-terminal region of human PTF1A. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PTF1A |
|---|---|
| Alternative Names | Pancreas transcription factor 1 subunit alpha Class A basic helix-loop-helix protein 29 bHLHa29 Pancreas-specific transcription factor 1a bHLH transcription factor p48 p48 DNA-binding subunit of transcription factor PTF1 PTF1-p48 PTF1A BHLHA29 PTF |
| Molecular Weight(MW) | 35 kDa |
Application
Western blot analysis in K562 cell line lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
