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PTGDS Antibody

Catalog Number:OM289137
OM289137
Discount Price
OM289137-100ul
1~2 Week
100ul
OM289137-50ul
50ul
OM289137-20ul
20ul
1~2 Week
Product Profile
Product Name PTGDS Antibody
Antibody Type Primary Antibodies
Antigen Alias PTGDS, PDS, PGD2, PGDS, PGDS2, LPGDS, L-PGDS
Product description PTGDS is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation.The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.1) Lovell, M.A., (2008) Neurology 70 (23), 2212-2218.
Immunogen Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PTGDS.
Key Feature
Clonality Polyclonal
Host Species Rabbit
Tested Applications ELISAIHCWB
PTGDS antibody can be used for detection of PTGDS by ELISA at 1:62500. PTGDS antibody can be used for detection of PTGDS by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Species Reactivity Human
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol PTGDS
Alternative Names PTGDS
PDS
PGD2
PGDS
PGDS2
LPGDS
L-PGDS
Molecular Weight(MW) 21 kDa
Database Links
Entrez Gene 5730
Protein Accession NP_000945
Application

Application

Antibody used in WB on Human HepG2 at 1 ug/ml.

Application

Antibody used in IHC on Human kidney.
Positive Control 1) Cat. No. 1211 - HepG2 Cell Lysate
Application Notes PTGDS antibody can be used for detection of PTGDS by ELISA at 1:62500. PTGDS antibody can be used for detection of PTGDS by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form Liquid
Storage Instructions For short periods of storage (days) store at 4˚C. For longer periods of storage, store PTGDS antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
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