Application
Antibody used in WB on Transfected 293T at 0.2-1 ug/ml.Application
Antibody used in IHC on Human kidney.| Product Name | PTPN2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PTPN2, PTPT, TC-PTP, TCELLPTP, TCPTP, PTN2 |
| Product description | PTPN2 is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling.The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Three alternatively spliced variants of this gene, which encode isoforms differing at their extreme C-termini, have been described. The different C-termini are thought to determine the substrate specificity, as well as the cellular localization of the isoforms. Two highly related but distinctly processed pseudogenes that localize to distinct chromosomes have been reported. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PTPN2. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHCWB |
| PTPN2 antibody can be used for detection of PTPN2 by ELISA at 1:312500. PTPN2 antibody can be used for detection of PTPN2 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PTPN2 |
|---|---|
| Alternative Names | PTPN2 PTPT TC-PTP TCELLPTP TCPTP PTN2 |
| Molecular Weight(MW) | 25 kDa |
Application
Antibody used in WB on Transfected 293T at 0.2-1 ug/ml.
Application
Antibody used in IHC on Human kidney.| Positive Control | 1) Tranfected 293T Cell Lysate |
|---|---|
| Application Notes | PTPN2 antibody can be used for detection of PTPN2 by ELISA at 1:312500. PTPN2 antibody can be used for detection of PTPN2 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store PTPN2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
