Nectins (e.g., PVRL1; MIM 600644) are immunoglobulin-like
adhesion molecules that interact with afadin (AF6; MIM 159559).
Afadin is an actin filament-binding protein that connects nectins
to the actin cytoskeleton. The nectin-afadin system organizes
adherens junctions cooperatively with the cadherin (see MIM
192090)-catenin (see MIM 116805) system in epithelial
cells.1) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Immunogen
This PVRL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 507-536 amino acids from the C-terminal region of human PVRL3.
Western blot analysis in MCF-7 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.