Cell cycle checkpoint protein RAD1, hRAD1, DNA repair exonuclease rad1 homolog, Rad1-like DNA damage checkpoint protein, RAD1, REC1
Product description
This gene encodes a component of a heterotrimeric cell
cycle checkpoint complex, known as the 9-1-1 complex, that is
activated to stop cell cycle progression in response to DNA damage
or incomplete DNA replication. The 9-1-1 complex is recruited by
RAD17 to affected sites where it may attract specialized DNA
polymerases and other DNA repair effectors. Alternatively spliced
transcript variants of this gene have been described. [provided by
RefSeq].1) Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
Immunogen
This RAD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-146 amino acids from the Central region of human RAD1.
Western blot analysis in K562 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.