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RAGE Antibody

Catalog Number:OM289474
OM289474
Discount Price
OM289474-100ul
1~2 Week
100ul
OM289474-50ul
50ul
OM289474-20ul
20ul
1~2 Week
Product Profile
Product Name RAGE Antibody
Antibody Type Primary Antibodies
Product description AGER is a member of the immunoglobulin superfamily of cell surface molecules. It is a receptor for various molecules, including the amyloidogenic form of serum amyloid A, amyloid-beta protein, members of the S100/calgranulin superfamily and advanced glycation end products.1) Schlueter, C., et al., Biochim. Biophys. Acta 1630(1):1-6 (2003). Shanmugam, N., et al., J. Biol. Chem. 278(37):34834-34844 (2003). Kuniyasu, H., et al., Oncol. Rep. 10(2):445-448 (2003). Hsieh, H.L., et al., Biochem. Biophys. Res. Commun. 307(2):375-381 (2003). Rocken, C., et al., Am. J. Pathol. 162(4):1213-1220 (2003).
Immunogen This RAGE (AGER) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-59 amino acids from the N-terminal region of human RAGE (AGER).
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications IHC-PWB
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100
Species Reactivity HumanMouse
Concentration 1mg/ml
Purification Unpurified
Target Information
Gene Symbol AGER
Alternative Names Advanced glycosylation end product-specific receptor
Receptor for advanced glycosylation end products
AGER
RAGE
Molecular Weight(MW) 43 kDa
Database Links
Entrez Gene 177
Protein Accession Q15109
Application

Application

Western blot analysis of AGER-K44 in mouse lung tissue lysates (35ug/lane)

Application

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma; HC = hepatocarcinoma.
Application Notes For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100
Additional Information
Form Liquid
Storage Instructions Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.
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