RALBP1 plays a role in receptor-mediated endocytosis and
is a downstream effector of the small GTP-binding protein RAL (see
RALA; MIM 179550). Small G proteins, such as RAL, have GDP-bound
inactive and GTP-bound active forms, which shift from the inactive
to the active state through the action of RALGDS (MIM 601619),
which in turn is activated by RAS (see HRAS; MIM 190020) (summary
by Feig, 2003 [PubMed 12888294]).1) Singhal, S.S., et al. Int. J. Cancer 126(6):1327-1338(2010)
Immunogen
This RALBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-71 amino acids from the N-terminal region of human RALBP1.
Western blot analysis in MCF-7 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.